陈子林（CHEN, Zilin），男，毕业于东京都立大学，研究生学历，现任武汉大学珞珈学者特聘教授、博士生导师、药学专业院副院长、药物分析与筛选研究所所长、药学实验中心主任。
人物经历
教育经历
工作经历
历任江西工业大学助教（ 1984 － 1988 ）
中德联合研究院讲师（ 1991 － 1996 ）
东京都立大学日本学术振兴会 (JSPS)特别研究员（ 2000 － 2002 ）
日本NTT先端技术综合研究所博士后研究员（ 2002 － 2004 ）
美国圣母玛利亚大学 (University of Notre Dame) 研究助理教授（ 2004 － 2007，2）
现任武汉大学珞珈学者特聘教授、博士生导师、药学院副院长、药物分析与筛选研究所所长、药学实验中心主任。
主要成就
科研成就
研究领域
研究兴趣与方向
生物及药物样品的微柱色谱、电泳分离及其与质谱联用技术
微/纳流控分析装置的研制及集成化
生物传感器及药物分子识别材料
疾病诊断标记物的分析新方法
药物筛选与质量控制
药物代谢动力学
论文
2014
1. H. Zhao, Z. Chen*, Screening of neuraminidase inhibitors from traditional Chinese medicines by integrating capillary electrophoresis with immobilized enzyme microreactor, J. Chromatogr. A, 1340(2014)139-145.
2. W. Zhang, Z. Zhang, J. Zhang, J. Meng, T. Bao, Z. Chen*, Covalent immobilization of graphene onto stainless steel wire for jacket-free stir bar sorptive extraction, J.Chromatogr. A, 1351(2014)12-20.
3. J. Zhang, W. Zhang, T. Bao, Z. Chen*, Enhancement of capillary electrochromatographic separation 表演 by conductive polymer in a layer-by-layer fabricated graphene stationary phase, J. Chromatogr. A,1339(2014)192-199.
4. W. Zhang, Z. Zhang, J. Meng, W. Zou, Z. Chen*, Adsorptive behavior and 固体-phase microextraction of bare stainless steel sample loop in high performance 羧基液体丁腈橡胶 chromatography, J. Chromatogr. A, 1365(2014)19-28.
5. J. Zhang, W. Zhang, T. Bao, Z. Chen*, Mussel-inspired polydopamine-assisted 羟基磷灰石 as stationary phase for capillary electrochromatography, Analyst, 139(2014)242-250.
6. H. Zhao, Z. Chen*, Screening of neuraminidase inhibitors from traditional Chinese medicines by transverse diffusion mediated capillary electrophoresis, Biomicrofluidics, 8 (2014) 052003
7. L. Ren, H. Zhao, Z. Chen*, Study on pharmacokinetic and tissue distribution of lycorine in mice 等离子体 and tissues by 羧基液体丁腈橡胶 chromatography–质量 spectrometry, Talanta, 119(2014)401-406
8. Y. Chen, Q. Xiang, Z. Chen*, Simultaneous and highly sensitive quantification of five bioactive components in Fructus Psoraleae and in rat 等离子体 by HPLC with fluorescent detection, Anal. Methods, 2014, 6 (1), 269 - 275
9. J. Chen, J. Zhang, W. Zhang, Z. Chen*, Sensitive determination of potential biomarker sarcosine for prostate cancer by 羧基液体丁腈橡胶 chromatography-mass spectrometry with DCC derivatization, J. Sep. Sci. 37(2014)14-19.
10. Y. Long, W. Zhang, F. Wang, Z. Chen*,Simultaneous determination of three curcuminoids in 姜黄属 longa L. by high performance 羧基液体丁腈橡胶 chromatography coupled with electrochemical detection, J. Pharm. Anal. 4(2014)325-330
11. W. Zhang†, W. Zhou†, Z. Chen,Graphene/polydopamine-modified polytetrafluoro乙烯 micro-tube for sensitive determination of three active components in Fructus Psoraleae by online 固体phase microextraction-high performance 羧基液体丁腈橡胶 chromatography, J. Sep. Sci. 2014, in press. (†co-first author)
12. W. Ma, P. Gao, J. Fan, Y. Hashi*, Z. Chen*,Determination of breath gas composition of lung cancer patients using gas chromatography/质量 spectrometry with monolithic material sorptive extraction, Biomedical Chromatography, 2014, in press.
13. 13. Q. Xiang, Y. Chen, Z. Chen*, Sensitive and simultaneous determination of active components in Lycoris radiata by high-performance 羧基液体丁腈橡胶 chromatography with 荧光 detection, Anal. Methods, 2014, in press.
2013
1. W. Zhang, J. Zhang, T. Bao, W. Zhou, J. Meng, Z. Chen*, Universal multilayer assemblies of graphene in chemically resistant micro-tubes for microextraction, Anal. Chem. 85(2013)6845-6854.
2. L. Wang, P. Hu, X. Deng, F. Wang, Z. Chen*, Fabrication of Electrochemical NO sensor Based on Nanostructured Film and Its Application in Drug Screening, Biosensors \u0026 Bioelectronics, 50(2013)57-61.
3. W. Ma, S. Fu, Y. Hashi, Z. Chen*, Determination of chiral jasmonates in flowers by GC-MS after monolithic material sorptive extraction, J.Agric \u0026 Food Chem. 61(2013)6288-6292.
4. H. Zhao, Z. Chen*, Screening of aromatase inhibitors from traditional Chinese medicines by electrophoretically mediated microanalysis in partially filled capillary, J. Sep. Sci. 36(2013)2691-2697.
5. W. Zhang, Z. Chen*, Mussel inspired polydopamine functionalized poly(ether ether ketone) tube for online 固体phase microextraction-high performance 羧基液体丁腈橡胶 chromatography and its application in analysis of proto小檗碱 alkaloids in rat 等离子体, J. Chromatogr. A, 1278(2013)29-36.
6. W. Zhang, J. Du, C. Su, L. Zhu, Z. Chen*, Development of β-cyclodextrin- modified silica and polyporous polymer particles for 固体phase extraction of 甲基 jasmonate in aqueous and plant samples, Anal. Lett. 46(2013) 900-911.
7. F. Wang, X. Sun, Y. Chen, S. Xie, Z. Chen*,Non-enzymatic Glucose Sensor Based on 铜 Nanoparticles Modified Microelectrode, Nanosci. and Nanotech. Lett, 5(2013)624-629.
8. J. Liu, J. Zhang, Z. Chen*, Determination of bavachinin enantiomers in Fructus Psoraleae and rat 等离子体 by liquid chromatography using per甲基ated-β-CD as a chiral selector, J. Pharm. Anal. 5(2013) 349-353.
9. X. Mou, W. Zhang, Z. Chen*，Highly selective extraction of baicalin in natural herbs and medicinal preparations by molecularly imprinted 均聚物, J. Applied Polymer Sci. 130(2013)1873-1878.
10. Y. Rang, W. Zhang, Z. Chen*, Determination of 犬尿氨酸 and 色氨酸 in human 等离子体 by stacking-micellar electrokinetic chromatography, Anal.Lett. 46(2013)2503-2513.
11. H. Zhao, Z. Chen*, An HPLC-ESI-MS method for Analysis of loureirin A and B in dragon’s blood and Application in Pharmacokinetics and tissue distribution in rats, Fitoterapia, 86(2013)149-158.
12. Y. Zhang, Z. Chen*, Nonaqueous Capillary Electrophoresis Electrospray Ionization-Ion Trap-质量 Spectrometric Analysis of 石蒜科 Alkaloids, J. Sep.Sci. 36(2013)1078-1084.
13. Y. Chen, Z. Chen*, Simultaneous separation of jasmonic acid conjugates with amino acids by micellar electrokinetic chromatography, J. Sep. Sci., 36(2013)892-897.
14. J. Zhang, Z. Chen*, Determination of matrine and oxymatrine in Sophora Flavescens by non-aqueous capillary electrophoresis-electrospray ionization-ion trap-质量 spectrometry, Anal. Lett. 46(2013)651-662.
15. Q. Chen, W. Zhang, Y. Zhang, J. Chen, Z. Chen*, Identification and quantification of active alkaloids in Catharanthus roseus by 羧基液体丁腈橡胶 chromatography-ion trap 质量 spectrometry, Food Chem. 139(2013)845-852.
16. Y. Chen, Z. Chen*, Fluorescein-core piperazine as a fluorescent labeling reagent for highly sensitive determination of jasmonic acid by high-performance 羧基液体丁腈橡胶 chromatography, Anal. Method, 5(2013)1733-1738.
17. Q. Chen, J. Zhang, W. Zhang, Z. Chen*, Analysis of active alkaloids in family Menispermaceae by nonaqueous capillary electrophoresis- ion trap 质量 spectrometry, J. Sep. Sci. 36(2013)341-349.
18. S. Xie, F. Wang, Z. Chen*, Determination of Endogenous Jasmonic Acid in Plant Samples by 羧基液体丁腈橡胶 Chromatography-Electrochemical Detection Based on Derivatization with Dopamine, Analyst, 128(2013)1226-1231.
19. W. Zhang, Z. Chen*, A 均聚物 monolith microextraction coupled with HPLC for determination of jasmonates in wintersweet flowers, Anal. Lett. 46(2013)74-86.
20. W. Zhang, Z. Chen*, Preparation of micropipette tip-based molecularly imprinted monolith for selective micro-solid phase extraction of berberine in 等离子体 and urine samples, Talanta, 103(2013)103-109.
2012
1. J. Zhang, T. Bao, Z. Chen*, Determination of polycyclic aromatic hydrocarbons on polymeric SMA-EGDMA mononlith column by capillary electrochromatography, Anal. Method. 4(2012)4140-4145.
2. J. Chen, Q. Chen, Z. Chen*Enhancing Sensitivity of 羧基液体丁腈橡胶 Chromatographic/Ion-trap 质量 Spectrometric Determination of Jasmonic Acid by Derivatization with N, N –Dicyclohexylcarbodiimide, Analyst,137( 2012)5436-5440.
3. Y. Wu, W. Zhang, Z. Chen*, A poly (4-vinylpridine-co-ethylene glycol dimethacrylate) monolithic concentrator for in-line concentration-capillary electrophoresis analysis of phenols in H₂O samples, Electrophoresis, 33(2012)2911-2919.
4. X. Dang, C. Dang, Z. Chen, S. Wang, S. Hu, Electrochemical characteristics of cis-jasmone in acid media at multi-wall 碳 nanotube-Nafion composite film modified electrode and its analytical application, Electrochem. Acta, 81(2012)239-245.
5. Y. Zhang, Z. Chen*, Separation of isomeric bavachin and isobavachalcone in the Fructus Psoraleae by capillary electrophoresis-electrospray-质量 spectrometry, J. Sep. Sci. 35(2012)1644-1650.
6. L. Liu, Z. Chen*, Analysis of four alkaloids of Coptis chinensis in rat 等离子体 by high performance 羧基液体丁腈橡胶 chromatography with electrochemical detection, Anal. Chim. Acta, 737(2012)99-104.
7. S. Fu, J. Fan, Y. Hashi*, Z. Chen*, Determination of polycyclic aromatic hydrocarbons in H₂O samples using online microextraction by packed sorbent coupled with gas chromatography-质量 spectrometry, Talanta, 94(2012)152-157.
8. Y. Zhang, L. Huang, Q. Chen, Z. Chen*, A silica monolithic column chemically bonded L-pipecolic acid as chiral stationary phase for enantiomeric separations of dansyl 氨基 acids by capillary electrochromatography-质量 spectrometry, Chromatographia, 75(2012)289-296.
9. Q.Chen, Y. Li, Z. Chen*, Separation, identification and quantification of active constituents in Fructus Psoraleae by high-performance 羧基液体丁腈橡胶 chromatography with UV, ion trap 质量 spectrometry and electrochemical detection, J. Pharma. Anal. 2(2012)143-151.
10. L. Liu, S. Li, Z. Chen*, Simultaneous determination of 汉防己甲素 and fangchinoline in herbal medicine Stephania tetrandra S. Moore by 羧基液体丁腈橡胶 chromatography with electrochemical detection, J. Pharma.\u0026 Biomed. Anal. 61(2012)251-255.
2011
1. F. Yan, F. Wang, Z. Chen*, label-free aptamer-based biofunctional electtrochemical biosensor for thrombin and adenosine, Sensors and Actuators B Chemical. 160(2011)1380-1385.
2. Q. Chen, N. Li, W. Zhang, J. Chen and Z. Chen*, Simultaneous determination of 长春碱 and its monomeric precursors vindoline and catharanthine in Catharanthus roseus by capillary electrophoresis-质量 spectrometry, J. Sep. Sci. 34(2011)2885-2892
3. Q. Chen, Y. Zhang, W. Zhang, Z. Chen*, Identification and quantification of oleanolic acid and ursolic acid in Chinese herbs by 羧基液体丁腈橡胶 chromatography-ion trap 质量 spectrometry, Biomed. Chromatogr. 25(2011)1381-1388.
4. Q. Chen, S. Luo, Y. Zhang, Z. Chen*, Development of a liquid chromatography-mass spectrometry method for the determination of ursolic acid in rat plasma and tissue: Application to the pharmacokinetic and tissue distribution study, Anal. Bioanal Chem. 399(2011)2877-2884.
5. Y. Li, F. Wang, Z. Chen*, Determination of bavachin and isobavachalcone in Fructus Psoraleae by high-performance 羧基液体丁腈橡胶 chromatography with electrochemical detection, J. Sep. Sci. 34(2011) 514-519.
6. F. Wang, X. Chen, Z. Chen*, Eletrodeposited nickel 氧化物 on a film of 碳 nanotubes
For monitoring nitric oxide release from rat 肾脏 and drug samples，Microchim. Acta, 173(2011)65-72.
7. L. Liu, Y. Chen, Y. Zhang, F. Wang and Z. Chen*, Determination of 色氨酸 and kynurenine in human 等离子体 by 羧基液体丁腈橡胶 chromatography-electrochemical detection with multi-wall 碳 nanotube-modified glassy carbon electrode, Biomed. Chromato., 25(2011)938-942.
8. F. Wang, X. Deng, W. Wang, Z. Chen*, Nitric 氧化物 measurement in biological and pharmaceutical samples by a novel electrochemical sensor, J. 固体 State Electrochem., 15(2011)829-836.
9. L. Yang, Z. Chen*, Direct evaluation of 配体-receptor interaction by a novel imaging model based on fluorescent silica nanoparticle as ligand probe and molecular imprinting 均聚物 as artificial receptor, Anal. Lett. 44(2011)687-697
10. Tian Gan, Chengguo Hu, Zilin Chen, Shengshui Hu, A disposable electrochemical sensor for the determination of indole–3–acetic acid based on poly(safranine T)–reduced graphene 氧化物 nanocomposite, Talanta，85(2011)310-316
11. Tian Gan, Chengguo Hu, Zilin Chen, Shengshui Hu, Novel electrocatalytic system for the oxidation of methyl jasmonate based on layer-by-layer assembling of 蒙脱石 and phosphotungstic acid nanohybrid on graphite electrode, Electrochimica Acta, 56(2011)4512-4517
12. X. Dang, C. Hu, Z. Chen，S. Hu, A novel electrochemical method for determination of cis-jasmone based on enhancement effect of cetyltrimethylammonium 溴化物, J. Electroanal. Chem., 657(2011)39-45
2010
1. W. Zhang, Y. Wu, Y. Chen, H. Jiang, Z. Chen*, Simultaneous separation of four metal ions by capillary electrophoresis using bis (2-pyridylmethyl) (8-pyridylmethyloxy-喹啉2-甲基)-amine as chelating agent, Chromatographia, 72(2010)1201-1205.
2. T. Gan, C. Hu, Z. Chen, S. Hu*, Direct electrochemical determination of methyl jasmonate in wheat spikelet at a nano-蒙脱石 film modified electrode by derivative square wavevoltammetry, J. Agric Food Chem.,58(2010)8942-8947.
3. T. Gan, C. Hu, Z. Chen, S. Hu*, Fabrication and application of a novel plant hormone sensor for the determination of 甲基 jasmonate based on self-assembling of phosphotungstic acid-graphene 氧化物 nanohybrid on graphite electrode, Sensor and Actuators B: Chemical, 151(2010)8-14.
4. Y. Liao, F. Wang, Z. Chen*, Electrochemical behavior and the determination of methyl jasmonates, Chinese Sci. Bull, 55(21)(2010)2225-2230
5. X. Deng, F. Wang Z. Chen*, A novel electrochemical sensor based on nano-structured film electrode for monitoring nitric oxide in living tissues, Talanta, 82(2010)1218-1224.
6. F. Wang, Y. Liao, Y. Ren, Z. Chen*, A novel method for D-arabinitol determination based on a nano-structured sensing film by one-step electrodeposition, Microchim. Acta, 17(2010)9-15, 2009.
7. Q. Chen, S. Weißig, S. Luo, Z. Chen*, Simultaneous determination of five anti-epilepsy drugs in human 等离子体 using 羧基液体丁腈橡胶 chromatography-质量 spectrometry, Sci China B Chem, 53(2010)2373-2378.
2009
1. L. Liu, Z. Chen*, “Separation of small molecular peptides with the same amino acid composition but different sequences by high performance 羧基液体丁腈橡胶 chromatography-electrospray ionization-质量 spectrometry”, Sci China B Chem, 52(12) (2009)2264-2268.
2. Y. Weng, Z. Chen*, F. Wang, L. Xue H. Jiang "High sensitive determination of zinc with novel H₂Osoluble small molecular fluorescent sensor" Anal. Chim. Acta, 647(2009) 215-218.
3. D. Feng, F. Wang, Z. Chen*, “Electrochemical glucose sensor based on one step construction of gold nanoparticle-chitosan composite film”, Sensors \u0026 Actuators: B. Chemical, 138 (2009) 539-544
4. Y. Wu, J. Xie, F. Wang, Z. Chen*, ‘Separation of small molecular peptides with same amino acid composition and different sequences by capillary electrophoresis’, J. Sep. Sci. 32(2009)437-440.
2008
1. X. Chen, F. Wang, Z. Chen*, “An electropolymerized Nile 蓝色 sensing film-based nitrite sensor and application in food analysis”, Anal. Chim.Acta, 623(2008)213-220.
2. Y. Wu, J. Xue, F. Wang, Z. Chen*, ‘Electrokinetic separation of peptides and proteins using polyvinylamine-coated capillary with UV and ESI-MS detections’, J. Sep. Sci. 31(2008) 814-823.
2007
1. Z. Chen, B. Boggess, H. C. Chang, ‘Open-tubular capillary electrochromatography-mass spectrometry with sheathless nanoflow electrospray ionization for analysis of amino acids and peptides’, J. 质量 Spec. 42(2007)244-253.
2. Z. Chen, F.-C. Hsu, D. Battigelli, H. C. Chang, ‘Capture and release of 病毒 using amino-funcitonalized silica particles, Anal. Chim. Acta, 569(2006)76-82.
3. P. Wang, Z. Chen, and H. C. Chang, ‘An integrated micropump and electrospray emitter based on porous silica monliths’, Electrophoresis, 27(2006)3964-3970.
4. P. Wang, Z. Chen, and H. C. Chang, ‘A new electroosmotic pump based on silica monoliths’, Sensors and Actuators B, 113 (2006)500-509.
5. C. Hu, Z. Chen, A. Shen, X. Shen, J. Li, S.S.Hu, ‘H₂Osoluble single-walled 碳 nanotubes via noncovalent functionalization by rigid, planar and conjugated diazo dye’ Carbon, 44(2006)428-434.
6. Z. Chen, P. Wang, H. C. Chang, ‘An electroosmotic micro-pump based on monolithic silica for micro flow analyses and electrosprays’, Anal.\u0026 Bioanal. Chem., 382(2005)817-824.
7. Z. Chen, H. C. Chang, T. Hobo, ‘Application of monolithic silica matrix in microfluidic analysis’(invited), Bunseki Kagaku (Japanese Anal. Chem.), 54(2005)583.
8. Z. Chen, K. Hayashi, Y. Iwasaki, R. Kurita, O. Niwa, K. Sunagawa, ‘On-line monolithic enzyme reactor fabricated by sol-gel process for elimination of ascorbic acid while monitoring dopamine’, Electroanalysis. 17 (2005)231-238.
9. Z. Chen, K. Uchiyama, T. Hobo, ‘Chiral resolution of dansyl amino acids by ligand exchange capillary electrophoresis using Cu(II)-L-Prolinamides as chiral selectors’ Anal. Chim. Acta, 523(1)(2004)1-7.
10. Z. Chen, T. Fuyumuro, K. Watabe, T. Hobo, ‘Influence of spacers and organic modifiers on chromatographic behaviors on chiral diamide stationary phase with N-(3,5-Dimethylbenzoyl)-D-phenylglycine’ Anal. Chim. Acta, 518(1-2)(2004) 181-189.
11. Z. Chen, T. Nishiyama, K. Uchiyama, T. Hobo, ‘Electrochromatographic enantioseparation using chiral ligand exchange monolithic sol-gel column’ Anal. Chim. Acta, 501(1)(2004) 17-23.
12. T. You, O. Niwa, Z. Chen, K. Hayashi, M. Tomita, S. Hirono, ‘A novel amperometric detector formed of highly dispersed Ni nano-particles embedded in a graphite-like carbon film electrode for sugar determination’, Anal. Chem. 75 (2003) 5191-5196.
13. H. Ozawa, Z. Chen, K. Kawata, T. Nakagama, K. Uchiyama, T. Hobo, ‘Capillary electrochromatographic behaviors of dansyl amino acid enantiomers on cyclodextrin-immolilized monolithic silica column’, Bunseki Kagaku, (Japanese Anal. Chem.) 52(12)(2003)1105-1112.
14. T. Nishiyama, Z. Chen, T. Nakagama, K. Uchiyama, T. Hobo, ‘Separation of dansyl amino acid enantiomers by 配体 exchange capillary electrochromatography ushing L-lysinamide-modified monolithic silica column’, Bunseki Kagaku (Japanese Anal. Chem.), 52(2003)1005-1010.
15. Z. Chen, M. Niidzma, K. Uchiyama and T. Hobo, ‘Comparisons of enantioseparations using Cu(II) complexes with L-amino acid amides as chiral selectors or chiral stationary phases by CE, CEC and micro-LC’, J. Chromatogr. A, 990 (2003) 75-82.
16. Z. Chen, H. Ozawa, K. Uchiyama and T. Hobo, ‘Cyclodextrin-modified monolithic silica column for resolving of dansyl 氨基 acid enantiomers and positional isomers by capillary electrochromatography’, Electrophoresis, 24(15)(2003)2550-2558.
17. Z. Chen, T. Fuyumuro, T. Nakagama, K. Uchiyama and T. Hobo, ‘New diamide-type chiral stationary phase for chiral separations by normal and reverse phases HPLC’, J. 羧基液体丁腈橡胶 Chromatogr. \u0026 Related Tech., 26(13)(2003)2103-2117.
18. Z. Chen, T. Nakayama, T. Nakagama, K. Uchiyama and T. Hobo, ‘Thermodynamic Approaches to Intermolecular Interaction and Retention Behaviors in Liquid Chromatography’, J. 羧基液体丁腈橡胶 Chromatogr. \u0026 Relative Tech., 26(17)(2003)2809-2838.
19. Z. Chen, K. Uchiyama and T. Hobo, ‘Chemically modified chiral monolithic silica column for the enantioseparation by m-HPLC’, J. Chromatogr. A, 942(2002) 83-91.
20. Z. Chen, M. Niidzma, T. Nakagama, K. Uchiyama and T. Hobo, ‘Enantioseparations of dansyl amino acids unsing Cu(II) complexes with L-amino acylamides as chiral selectors in electrolytes by capillary electrophoresis’, J. Sep. Sci, 25(2002)1197-1201.
21. Z. Chen and T. Hobo, ‘Chemically L-phenylalaninamide-modified monolithic silica column prepared by sol-gel process for enantioseparation of dansyl amino acids by 配体 exchange-capillary electrochromatography’, Anal. Chem., 73 (2001) 3348-3357.
22. Z. Chen and T. Hobo, ‘Chemically L-prolinamide-modified monolithic silica column for enantiomeric separation of hydroxy acids and dansyl amino acids by capillary electrochromatography and m-HPLC’, Electrophoresis, 22 (2001) 3339-3346.
23. Z. Chen, K. Uchiyama and T. Hobo, ‘Interaction between 18-crown-6-tetracarboxylic acid and positional substituents of enantiomers and simultaneous separation of positional enantiomers of 甲基DL-色氨酸s by capillary electrophoresis’, Electrophoresis, 22 (2001) 2136-2142.
24. Z. Chen, K. Yamada, M. Niitsuma, K. Uchiyama and T. Hobo, ‘Separation selectivity in micellar electrokinetic chromatography using different anionic surfactants as pseudo-stationary phases’, Chromatographia, 54 (2001) 629-633.
25. Z. Chen, K. Uchiyama and T. Hobo, ‘18-crown-6-tetracarboxylic acid as a chiral additive for the simultaneous separation of o-, m- and p-enantiomers of phenylalanine family by capillary electrophoresis’, Enantiomer, 6 (2001) 19-25.
26. Z. Chen, ‘Ligand exchange-micellar electrokinetic chromatography and its applications’ (Digest of doctoral dissertation in Japanese), Bunseki Kagaku (Japanese Anal. Chem.), 49 (2000) 713-714.
27. Z. Chen, K. Uchiyama and T. Hobo, ‘Estimation of formation constants of ternary Cu(II) complexes with mixed amino acid enantiomers based on 配体 exchange by capillary electrophoresis’, Anal. Sci., 16(8) (2000) 837-841.
28. Z. Chen, K. Uchiyama and T. Hobo, ‘Separation of hydroxy acid enantiomers by ligand exchange-micellar electrokinetic chroamtography’ (in Japanese), Bunseki Kagaku (Japanese Anal. Chem.), 49(10) (2000) 759-764.
29. Z. Chen, J. Lin, K. Uchiyama and T. Hobo, ‘Determination of critical micelle concentration of anionic surfactants by ligand exchange micellar electrokinetic chromatography’, Anal. Chem. Acta, 403 (2000) 173-178.
30. Z. Chen, J. Lin, K. Uchiyama and T. Hobo, ‘Reversal behavior of the enantiomers migration order and the stereo-selectivity of Cu(II) complex with amino acid enantiomers in 配体exchange micellar electrokinetic chromatography’, Anal. Sci., 16(2) (2000) 131-137.
31. Z. Chen, J. Lin, K. Uchiyama and T. Hobo, ‘Simultaneous separation of sixteen positional and optical isomers of the tryptophan family by 配体-exchange micellar electrokinetic chromatography’, Chromatographia, 49 (1999) 436-443.
32. Z. Chen, J. Lin, K. Uchiyama and T. Hobo, ‘Separation behavior of amino acid enantiomers in ligand-exchange micellar electrokinetic chromatography’, J. Microcol. Sep., 11 (1999) 534-540.
33. Z. Chen, J. Lin, K. Uchiyama and T. Hobo, ‘Simultaneous separation of o-, m-, p-fluoro-DL-phenylalanine and o-, m-, p-DL-tyrosine by ligand exchange micellar electrokinetic capillary chromatography’, J. Chromatogr. A, 813 (1998) 369-378.
34. Z. Chen, G. Xu, K. Specht, R. Yang and S. She, ‘Determination of taurine in biological samples by reversed-phase 羧基液体丁腈橡胶 chromatography with precolumn derivatization with dinitrofluorobenzene’, Anal. Chim. Acta, 296 (1994) 249-253.
35. S. S. Hu, Z. Chen and T. Zhang, ‘Adsorptive stripping voltammetry of testosterone propionate in pharmaceutical preparations’, Fresenius’ J. Anal. Chem., 346 (10-11) (1993) 1008-10.
合著
合著专著 2 部 (Elsevier 出版社 , Transworld Research Network 出版社 )。
承担课题
在研项目：
1．国家自然科学基金面上项目：基于雌激素受体及芳香化酶靶向识别分析新方法 及其在抗乳腺癌药物分析中应用（Grant No. 21375101, 2014-2017）
2. 湖北省自然科学基金重点项目：新型固相微萃取-色谱-质谱联用技术及其在肿 瘤诊断标志物筛选中 应用（Grant No. 2014CFA077， 2014-2016)
3. 教育部博士点博导基金(Grant No. 20110141110024, 2012-2014)
4. 武汉市科技局应用基础研究计划项目：抗乳腺癌药物筛选与分析新技术（GrantNo：20140601001010057， 2014-2015）
已结题项目
1．国家自然科学基金重大研究计划重点项目：茉莉花酸类植物激素高效分离与高灵敏度检测及其在水稻颖花开放机理研究中应用（Grant No：90817103， 2009-2012）
2. 国家自然科学基金面上项目：二酰胺类手性硅胶整体柱技术及杂环化合物类手性药物分离分析新方法研究 (Grant No: 30973672, 2010-2012)
3．国家自然科学基金面上项目：新型毛细管电色谱－电喷雾离子化－质谱联用技术及其在生物与药物分析中的应用研究（Grant No:20775055, 2008-2010）
4．教育部留学回国人员启动基金（No.教外司留[2008]890）
5．中央高校专项研究基金 (Grant Nos: 306275547, 306275866, 2010-2011)
6．湖北省自然科学基金“基于生物传感识别中药有效成分筛选分析新方法”（Grant No 2011CDB475, 2011-2012)
7．武汉综合性新药研究开发技术大平台(参加。负责人：吴建国,No.2009ZX09301-14)
8. 武汉大学“珞珈学者特聘教授”启动基金（Grant Nos: 306276216, 306271159）
教学成就
1． 本科生课程：中药分析、仪器分析
2． 药学院研究生必修课程：药物分离与检测科学
药物分析专业研究生必修课程：药物分析前沿文献导读
3. 研究生班：综合药物分析
社会活动
Editorial board, Drug Discoveries \u0026 Therapeutics
Associate Editor, Journal of Pharmaceutical Analysis
编委, 医药导报
中国药学会药物分析专业委员会委员
教育部药学类专业教学指导委员会委员
国家留学基金评审专家
教育部留学回国人员启动基金评审专家
国家自然科学基金评审专家
武汉市医药行业协会常务副会长
获得荣誉
参考资料
名单曝光！武汉大学这94人入选“2022中国高被引学者榜单”，最具全球影响力！.今日头条.2023-04-03